Clinical correlates of hypotension in patients with acute organophosphorus poisoning

BACKGROUND The aim of the present study is to describe clinical correlates hypotension and its associated outcomes in patients with acute organophosphorus poisoning (AOPP). METHODS In this retrospective cohort study, we analyzed data pertaining 871 AOPP who were treated at two hospitals. Data from hypotensive non-hypotensive compared identify hypotension. We also evaluated association between parameters (including hypotension) in-hospital mortality. RESULTS incidence was 16.4%. Hypotensive showed significantly higher mortality (1.1% vs. 39.9%, P<0.001). Advanced age (odds ratio [OR] 1.25, 95% confidence interval [CI] 1.08-1.44), history diabetes (OR 2.65, CI 1.14-5.96), increased white blood cell count 1.06, 1.03-1.09), plasma cholinesterase 0.91, 0.84-0.94), albumin 0.88, 0.85-0.92), serum amylase 1.01, 1.01-1.02), pH 0.64, 0.54-0.75) After adjusting for potential confounders, (hazard 8.77-37.06, depending on controlled variables). CONCLUSIONS Hypotension a common complication age, diabetes, changes laboratory patients.